Download Clinical Strategies in the Management of Diabetic by Francesco Bandello, Marco Attilio Zarbin, Rosangela PDF

By Francesco Bandello, Marco Attilio Zarbin, Rosangela Lattanzio, Ilaria Zucchiatti

With the arrival of powerful remedies for diabetic retinopathy (DR), a brand new period within the administration of DR has been spread out. Amid the deluge of authorized remedies and promising new options, in spite of the fact that, clinicians may well locate it tricky to settle on the right perform in each one person case. the aim of this easy-to-use and richly illustrated handbook is to aid ophthalmologists in making judgements within the complete administration of DR in accordance with the easiest on hand facts. useful and entire strategies are supplied to lead clinicians in prognosis, decision-making, and remedy. The guide comprises functional algorithms and case histories with regards to all phases of DR that basically clarify the development of the ailment and should aid the clinician to settle on the easiest healing technique. it is going to be a great source for ophthalmologists aiming to supply optimum scientific administration for this sight-threatening disease.

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Additional info for Clinical Strategies in the Management of Diabetic Retinopathy: A step-by-step Guide for Ophthalmologists

Example text

Even if the advantages of tight glycemic control emerged from these studies, this approach could produce severe side effects, such as an early worsening of diabetic retinopathy. 6 % of patients with conventional insulin therapy [65]. However, within 18 months the effect disappeared without causing an important visual loss. Patients with greater risk of developing this complication had higher HbA1c levels at baseline and a faster reduction of HbA1c levels within 6 months (Fig. 24). Thus, it is important to choose a therapeutic strategy focused on a slow reduction of glycemic levels.

Today there are many classes of pharmacologic agents available for the treatment of diabetes. For insulin therapy, diabetic patients may use rapid-acting insulin analogs, needed to replace physiological postprandial insulin secretion, and long-acting insulin, designed to regulate the basal glycemic control. For patients with type 2 diabetes, generally, the first antidiabetic drug utilized is metformin, a biguanide, which acts in reducing hepatic glucose production; the other classes of insulin 44 F.

Lancet 376:124–136 16. Todd JA, Walker NM, Cooper JD et al (2007) Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet 39:857–864 17. Sladek R, Rocheleau G, Rung J et al (2007) A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445:881–885 18. Wild S, Roglic G, Green A, Sicree R, King H (2004) Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27:1047–1053 19.

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