Download Electrophysiology of Vision: Clinical Testing and by Byron L. Lam PDF

By Byron L. Lam

Written via an skilled clinician and researcher within the box, this reference presents useful details at the scientific recording ideas, physiologic origins, and functions of electroretinogram (ERG), electro-oculogram (EOG), and visible evoked power (VEP) assessments.

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Additional resources for Electrophysiology of Vision: Clinical Testing and Applications

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If photopic responses are recorded first, the number and intensity of the photopic flash stimuli should not be excessive. Otherwise the subsequent dark adaptation will need to be longer to allow for retinal recovery. When contact-lens type electrodes are used, the scotopic responses may be performed first to minimize patient discomfort. The electrodes are placed at the end of the dark-adaptation period under dim red illumination to avoid altering rod sensitivity but this light exposure must be minimized.

With the fovea at the center, this high-density rod zone is a donut-shaped, slightly elliptical retinal region with a long horizontal axis. Within this zone, the rod density reaches over 100,000 per mm2. The rods are found throughout the retina but are absent at the foveal center. The rods, cones, 48 Chapter 1 and ganglion cells are slightly denser in the superonasal retina than the inferotemporal retina. This asymmetric distribution reflects the asymmetry of the visual field and accounts in part for the relatively shortened nasal field.

18) (67). The R1 component is related to the conversion of lumirhodopsin to metarhodopsin I, and R2 is associated with the conversion of metarhodopsin I to metarhodopsin II. 5 msec. 18 Schematic drawing of early receptor potential (ERP). 75 msec, respectively. The ERP reflects changes in membrane potential at the outer segments of the photoreceptors due to transition of rhodopsin to its activated form. The ERP is not visible on routine ERG recordings because ERP is brief and buried in the stimulus-induced voltage artifact and optimal recordings of ERP require brief flashes much brighter than the standard flash.

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